Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888688 | 1.00 | MAPT (0.56) | MAPTTDP1LMNARECQLKDM4E | |
| SCHEMBL25358 | 0.91 | KDM4E (0.62) | MAPTTDP1LMNARECQLKDM4E | |
| SCHEMBL29402979 | 0.91 | KDM4E (0.62) | MAPTTDP1LMNARECQLKDM4E | |
| Hydrogen Sulfide SCHEMBL21332206 | 0.89 | KDM4E (0.60) | MAPTTDP1LMNARECQLKDM4E | |
| SCHEMBL21332207 | 0.87 | KDM4E (0.58) | MAPTTDP1LMNARECQLKDM4E | |
| SCHEMBL22883115 | 0.87 | MAPT (0.48) | MAPTTDP1LMNARECQLKDM4E | |
| SCHEMBL18078274 | 0.81 | MAPT (0.54) | MAPTTDP1LMNARECQLKDM4E | |
| SCHEMBL12161313 | 0.81 | MAPT (0.59) | MAPTTDP1LMNARECQLKDM4E | |
| SCHEMBL223594 | 0.81 | MEN1 (0.59) | MAPTTDP1LMNARECQLKMT2A | |
| SCHEMBL19456875 | 0.81 | KDM4E (0.55) | MAPTTDP1LMNARECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302744-A | Peptide conjugates of microtubule targeting agents as therapeutic agents | 赛博克萨3公司 | 2022-04-08 | — | — | CN | disclosed |