Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26031798 | 1.00 | ESR1 (0.48) | ESR1KDM4ELMNAEPHX2MCHR1 | |
| SCHEMBL9924682 | 0.82 | KDM4E (0.44) | ESR1KDM4ELMNAKMT2APOLB | |
| SCHEMBL15076059 | 0.80 | KDM4E (0.53) | ESR1KDM4ELMNAEPHX2KMT2A | |
| SCHEMBL25361465 | 0.80 | KDM4E (0.53) | ESR1KDM4ELMNAEPHX2KMT2A | |
| SCHEMBL8234410 | 0.78 | HDAC3 (0.61) | MCHR1MAPK1HDAC3HDAC6NCOR2 | |
| SCHEMBL25361995 | 0.76 | KDM4E (0.54) | ESR1KDM4ELMNAEPHX2KMT2A | |
| SCHEMBL21389659 | 0.75 | KDM4E (0.53) | ESR1KDM4ELMNAEPHX2POLB | |
| SCHEMBL19786751 | 0.75 | KDM4E (0.53) | ESR1KDM4ELMNAEPHX2POLB | |
| SCHEMBL9924679 | 0.74 | KDM4E (0.59) | ESR1KDM4ELMNAEPHX2KMT2A | |
| SCHEMBL22488360 | 0.73 | HDAC3 (0.58) | MCHR1KMT2APOLBMAPK1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156601-A1 | DIAGNOSTICS FOR DETECTING ECTO-5'-NUCLEOTIDASE (CD73) | Westfälische Wilhelms-Universität Münster (DE) | 2023-08-24 | — | — | WO | disclosed |