Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25362014 | 0.82 | ESR1 (0.48) | KDM4ELMNAESR1KMT2APOLB | |
| SCHEMBL26031798 | 0.82 | ESR1 (0.48) | KDM4ELMNAESR1KMT2APOLB | |
| SCHEMBL9924686 | 0.76 | KDM4E (0.54) | KDM4ELMNAESR1KMT2APOLB | |
| SCHEMBL11064771 | 0.72 | KDM4E (0.61) | KDM4ELMNAESR1KMT2APOLB | |
| SCHEMBL11064769 | 0.72 | KDM4E (0.61) | KDM4ELMNAESR1KMT2APOLB | |
| SCHEMBL30956297 | 0.72 | ALPG (0.53) | KDM4ELMNAESR1KMT2AALDH1A1 | |
| SCHEMBL24649642 | 0.72 | ALPG (0.53) | KDM4ELMNAESR1KMT2AALDH1A1 | |
| SCHEMBL9924679 | 0.71 | KDM4E (0.59) | KDM4ELMNAESR1KMT2APOLB | |
| SCHEMBL14392991 | 0.71 | KDM4E (0.59) | KDM4ELMNAESR1KMT2APOLB | |
| SCHEMBL10124090 | 0.71 | KDM4E (0.59) | KDM4ELMNAESR1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040626-B2 | Nanofibers and morphology shifting micelles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-05-26 | — | — | US | disclosed |
| US-9040626-B2 | Nanofibers and morphology shifting micelles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-05-26 | — | — | US | disclosed |
| US-20120149843-A1 | NANOFIBERS AND MORPHOLOGY SHIFTING MICELLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149843-A1 | NANOFIBERS AND MORPHOLOGY SHIFTING MICELLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149843-A1 | NANOFIBERS AND MORPHOLOGY SHIFTING MICELLES | MFAP1, LGALS4, TLN1 | KDM4E 2687/4885LMNA 62/4885ESR1 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.