Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363409 | 0.87 | ALDH1A1 (0.39) | MAP4K1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL30541681 | 0.87 | ALDH1A1 (0.39) | MAP4K1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL30541588 | 0.85 | MAPT (0.39) | MAP4K1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL30541604 | 0.85 | ALDH1A1 (0.36) | MAP4K1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL25365264 | 0.85 | ALDH1A1 (0.36) | MAP4K1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL25364050 | 0.85 | MAPT (0.39) | MAP4K1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL25366340 | 0.85 | ACVR1 (0.48) | MAP4K1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30541581 | 0.83 | MAPT (0.36) | MAP4K1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL25365577 | 0.83 | MAPT (0.36) | MAP4K1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL25364542 | 0.83 | MAP4K1 (0.39) | MAP4K1ALDH1A1TSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159153-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-24 | — | — | WO | disclosed |