Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20669370 | 0.99 | HPGD (0.50) | HPGDGPR119USP2SMN1; SMN2HRH3 | |
| SCHEMBL26699680 | 0.87 | GPR119 (0.43) | HPGDGPR119USP2SMN1; SMN2EPHX2 | |
| SCHEMBL20669374 | 0.87 | GPR119 (0.43) | HPGDGPR119USP2SMN1; SMN2EPHX2 | |
| SCHEMBL24480361 | 0.87 | GPR119 (0.43) | HPGDGPR119USP2SMN1; SMN2EPHX2 | |
| SCHEMBL30540043 | 0.87 | USP2 (0.59) | HPGDGPR119USP2SMN1; SMN2HRH3 | |
| SCHEMBL25366279 | 0.87 | USP2 (0.59) | HPGDGPR119USP2SMN1; SMN2HRH3 | |
| SCHEMBL25628680 | 0.86 | HPGD (0.41) | HPGDGPR119USP2SMN1; SMN2HRH3 | |
| SCHEMBL29059015 | 0.85 | HSD17B10 (0.46) | HPGDGPR119USP2SMN1; SMN2EPHX2 | |
| SCHEMBL940349 | 0.84 | HRH3 (0.48) | HPGDGPR119USP2SMN1; SMN2HRH3 | |
| SCHEMBL29059099 | 0.83 | HPGD (0.44) | HPGDGPR119SMN1; SMN2EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656782-B1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) | 2021-12-22 | — | — | EP | disclosed |
| EP-3656782-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019015644-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2019-01-24 | — | — | WO | disclosed |