Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 12/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25367061 | 0.78 | GPR119 (0.48) | HTR6 | |
| SCHEMBL25365445 | 0.76 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL30541632 | 0.76 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL25363328 | 0.76 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL31578498 | 0.76 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL30541582 | 0.75 | GPR119 (0.39) | PTGS2PTGS1 | |
| SCHEMBL25366333 | 0.75 | GPR119 (0.39) | PTGS2PTGS1 | |
| SCHEMBL30541618 | 0.74 | GPR119 (0.34) | PTGS2PTGS1 | |
| SCHEMBL25365993 | 0.74 | GPR119 (0.34) | PTGS2PTGS1 | |
| SCHEMBL4261152 | 0.70 | HTR2C (0.56) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159153-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-24 | — | — | WO | disclosed |