SCHEMBL25366928

SCHEMBL25366928

CCC1(C)C=Cc2c(O)cc(CCc3ccccc3)cc2O1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 3/20 0.50
▸ CNR1 P21554 3/20 0.50
▸ CNR2 P34972 3/20 0.50
▸ TRPV1 Q8NER1 3/20 0.50
▸ TRPV3 Q8NET8 3/20 0.50
▸ TRPV4 Q9HBA0 3/20 0.50
▸ TRPV2 Q9Y5S1 3/20 0.50
▸ SLC6A2 P23975 2/20 0.50
▸ SLC6A4 P31645 2/20 0.50
▸ LDHA P00338 1/20 0.50
▸ SLC6A3 Q01959 1/20 0.50
▸ TRPM8 Q7Z2W7 1/20 0.50
▸ ALOX5 P09917 1/20 0.40
▸ APP P05067 1/20 0.39
▸ XDH P47989 2/20 0.37
▸ PTGS1 P23219 1/20 0.37
▸ PTGS2 P35354 1/20 0.37
▸ ALOX15 P16050 2/20 0.36
▸ IGF1R P08069 1/20 0.36
▸ DAO P14920 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25367522 0.88 ALOX5 (0.50) TRPA1CNR1CNR2TRPV1TRPV3
SCHEMBL25367932 0.72 DAO (0.40) CNR1CNR2PTGS1PTGS2ALOX15
SCHEMBL22069530 0.71 CNR2 (0.67) TRPA1CNR1CNR2TRPV1TRPV3
SCHEMBL31545686 0.69 CNR1 (0.49) TRPA1CNR1CNR2TRPV1TRPV3
SCHEMBL21348201 0.69 SLC6A2 (0.85) TRPA1CNR1CNR2TRPV1TRPV3
SCHEMBL21954902 0.69 CNR1 (0.52) TRPA1CNR1CNR2TRPV1TRPV3
SCHEMBL22095688 0.69 SLC6A2 (0.85) TRPA1CNR1CNR2TRPV1TRPV3
SCHEMBL21365703 0.69 SLC6A2 (0.85) TRPA1CNR1CNR2TRPV1TRPV3
SCHEMBL19926334 0.69 CNR1 (0.52) TRPA1CNR1CNR2TRPV1TRPV3
SCHEMBL31544956 0.69 CNR1 (0.52) TRPA1CNR1CNR2TRPV1TRPV3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250160327-A1 USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS ECOLE POLYTECHNIQUE (FR) 2025-05-22 — — US disclosed
EP-4478885-A1 USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS Ecole Polytechnique (FR) 2024-12-25 — — EP disclosed
CN-118973398-A Use of chromenes or chromane derivatives as herbicides 巴黎综合理工学院 2024-11-15 — — CN disclosed
WO-2023156464-A1 USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS ECOLE POLYTECHNIQUE (FR) 2023-08-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250160327-A1 USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS CBX8, CBX3, CDYL TRPA1 4073/4885CNR1 1081/4885CNR2 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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