Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22105163 | 0.80 | CNR1 (0.49) | PTGS2HPGDCNR1CNR2 | |
| SCHEMBL31759056 | 0.80 | CNR1 (0.49) | PTGS2HPGDCNR1CNR2 | |
| SCHEMBL25367522 | 0.73 | ALOX5 (0.50) | CNR1CNR2 | |
| SCHEMBL25366928 | 0.72 | TRPA1 (0.50) | DAOIGF1RALOX15PTGS1PTGS2 | |
| Stilbostemin B SCHEMBL31039665 | 0.67 | IGF1R (0.52) | DAOIGF1RALOX15PTGS2ALDH1A1 | |
| SCHEMBL716420 | 0.66 | IGF1R (0.55) | DAOIGF1RALOX15KDM4EBCL2 | |
| SCHEMBL31540969 | 0.64 | IGF1R (0.53) | DAOIGF1RALOX15PTGS2HPGD | |
| SCHEMBL16661546 | 0.63 | AHR (0.53) | DAOIGF1RALOX15PTGS2ALDH1A1 | |
| SCHEMBL9744485 | 0.61 | ALOX15 (0.84) | IGF1RALOX15PTGS1PTGS2ALDH1A1 | |
| SCHEMBL4648373 | 0.61 | ALDH1A1 (0.58) | ALOX15ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250160327-A1 | USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS | ECOLE POLYTECHNIQUE (FR) | 2025-05-22 | — | — | US | disclosed |
| EP-4478885-A1 | USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS | Ecole Polytechnique (FR) | 2024-12-25 | — | — | EP | disclosed |
| CN-118973398-A | Use of chromenes or chromane derivatives as herbicides | 巴黎综合理工学院 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023156464-A1 | USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS | ECOLE POLYTECHNIQUE (FR) | 2023-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250160327-A1 | USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS | CBX8, CBX3, CDYL | DAO 1095/4885IGF1R 2465/4885ALOX15 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.