SCHEMBL25367283

SCHEMBL25367283

Cn1nc2c(c1S(=O)(=O)Cl)COCC2

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
WNT3A P56704 3/20 0.32
TNKS2 Q9H2K2 3/20 0.32
F12 P00748 5/20 0.31
F2 P00734 1/20 0.31
CYP1A2 P05177 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25371542 0.78 POLB (0.45) POLBMAPTTDP1L3MBTL1CYP1A2
SCHEMBL16920673 0.74 POLB (0.35) POLBMAPTTDP1L3MBTL1WNT3A
SCHEMBL13684195 0.63 F12 (0.33) POLBF12CYP1A2GAA
SCHEMBL21836693 0.60 MTOR (0.31) WNT3ATNKS2F12
SCHEMBL24598682 0.60 F12 (0.49) F12F2
SCHEMBL16920684 0.60 F12 (0.32) F12
SCHEMBL31587277 0.59
SCHEMBL19153034 0.59 PDK1 (0.32)
SCHEMBL9202089 0.59 KDM4E (0.41) L3MBTL1
SCHEMBL17501753 0.58 UGCG (0.38) POLBMAPTTDP1L3MBTL1F12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250152574-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-15 US disclosed
CN-119731156-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-03-28 CN disclosed
EP-4479384-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2024-12-25 EP disclosed
WO-2023154499-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-17 WO disclosed
WO-2023154499-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152574-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP POLB 1375/4885MAPT 2725/4885TDP1 1753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.