SCHEMBL9202089

SCHEMBL9202089

Cc1nn(C)c(S(=O)(=O)Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
NMT1 P30419 2/20 0.35
KMT2A Q03164 2/20 0.33
GLS O94925 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GALR3 O60755 1/20 0.33
NR2F2 P24468 1/20 0.33
RAB9A P51151 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
ENPP3 O14638 2/20 0.32
ALPL P05186 2/20 0.32
XIAP P98170 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13683113 0.83 KDM4E (0.41) KDM4EL3MBTL1SMN1; SMN2NMT1KMT2A
SCHEMBL9201775 0.82 KDM4E (0.43) KDM4EL3MBTL1SMN1; SMN2NMT1KMT2A
SCHEMBL27281860 0.73 KDM4E (0.43) KDM4EL3MBTL1SMN1; SMN2KMT2AMEN1
SCHEMBL27034470 0.73
SCHEMBL9195475 0.72 PKM (0.54) KDM4ESMN1; SMN2KMT2AMEN1LMNA
SCHEMBL388129 0.71 L3MBTL1 (0.43) L3MBTL1NMT1ALDH1A1
SCHEMBL30845963 0.69 FPR2 (0.35) KDM4ESMN1; SMN2KMT2ALMNAALDH1A1
SCHEMBL347771 0.68 TSHR (0.44) NMT1KMT2ALMNAALDH1A1
SCHEMBL9197044 0.68 KDM4E (0.42) KDM4EL3MBTL1SMN1; SMN2KMT2ALMNA
SCHEMBL10577837 0.68 PDE4D (0.43) KDM4EL3MBTL1SMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6056792-A None JP disclosed
EP-4558481-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-28 EP disclosed
CN-119855809-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-18 CN disclosed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 WO disclosed
EP-0087780-B2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL IND LTD (JP) 1995-02-15 EP disclosed
JP-H0656792-A PYRAZOLE SULFONYLUREA DERIVATIVE AND PRODUCTION THEREOF AND SELECTIVE HERBICIDE CONTAINING THE DERIVATIVE NISSAN CHEM IND LTD 1994-03-01 JP disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
US-4872901-A PREFERENTIAL TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-10 US disclosed
EP-0220695-A1 Herbicidal compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-05-06 EP disclosed
EP-0087780-A2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1983-09-07 EP disclosed
JP-H00656792-A 0001-01-01 JP disclosed