Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 11/20 | 1.00 |
| ▸ | PADI1 | Q9ULC6 | 8/20 | 1.00 |
| ▸ | PADI2 | Q9Y2J8 | 6/20 | 1.00 |
| ▸ | PDE4A | P27815 | 3/20 | 0.89 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.89 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.89 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.89 |
| ▸ | PADI3 | Q9ULW8 | 6/20 | 0.82 |
| ▸ | PADI6 | Q6TGC4 | 2/20 | 0.70 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392045 | 0.94 | PADI4 (1.00) | PADI4PADI1PADI2PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL29636638 | 0.90 | PADI4 (1.00) | PADI4PADI1PADI2PDE4APDE4B | |
| SCHEMBL31378276 | 0.82 | PADI4 (1.00) | PADI4PADI1PADI2PDE4APDE4B | |
| SCHEMBL31378277 | 0.82 | PADI4 (1.00) | PADI4PADI1PADI2PDE4APDE4B | |
| SCHEMBL30228663 | 0.82 | PADI4 (1.00) | PADI4PADI1PADI2PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL18730598 | 0.79 | PADI4 (0.66) | PADI4PADI1PADI2PDE4APDE4B | |
| SCHEMBL1736671 | 0.74 | C3AR1 (0.81) | PADI4PADI1PADI2PDE4APDE4B | |
| SCHEMBL29402239 | 0.74 | C3AR1 (0.81) | PADI4PADI1PADI2PDE4APDE4B | |
| SCHEMBL1981102 | 0.74 | PADI4 (0.65) | PADI4PADI1PADI2PDE4APDE4B | |
| SCHEMBL4181143 | 0.73 | PADI1 (0.62) | PADI4PADI1PADI2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265432-A1 | METHODS AND COMPOSITIONS FOR TREATING ACUTE MYELOID LEUKEMIA | Sanford Burnham Prebys Medical Discovery Institute | 2023-08-24 | — | — | US | disclosed |