Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 5/20 | 0.62 |
| ▸ | PADI4 | Q9UM07 | 5/20 | 0.62 |
| ▸ | PADI2 | Q9Y2J8 | 4/20 | 0.62 |
| ▸ | PDE4A | P27815 | 3/20 | 0.62 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.62 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | CTSG | P08311 | 2/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | CMA1 | P23946 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12809901 | 0.89 | PRSS1 (0.56) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL186935 | 0.88 | CA2 (0.68) | CA2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL10668269 | 0.88 | CA2 (0.68) | CA2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL186937 | 0.88 | CA2 (0.68) | CA2PRSS1CTSGCTRB1CMA1 | |
| Ammonia Solution, Strong SCHEMBL11218438 | 0.86 | CA2 (0.67) | CA2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL28281357 | 0.85 | HPGDS (0.67) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL2569798 | 0.85 | HPGDS (0.67) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL24064866 | 0.83 | CA2 (0.63) | CA2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL18395838 | 0.83 | PADI1 (0.57) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL3903550 | 0.82 | PRSS1 (0.55) | CA2PRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124619-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124619-A1 | NOVEL COMPOUNDS | TRPV4, TRPC4, TRPV1 | PADI1 4553/4885PADI4 3910/4885PADI2 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.