SCHEMBL25368902

SCHEMBL25368902

c1cc2c(c(-c3ccc4nc[nH]c4c3)c1)CCNC2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 4/20 0.51
QPCTL Q9NXS2 4/20 0.51
IRAK4 Q9NWZ3 1/20 0.45
PRCP P42785 1/20 0.42
PRKCI P41743 1/20 0.41
CD44 P16070 1/20 0.41
ALOX5AP P20292 2/20 0.40
FEN1 P39748 2/20 0.40
MAPKAPK2 P49137 1/20 0.40
PRMT5 O14744 1/20 0.40
WDR77 Q9BQA1 1/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NMT1 P30419 1/20 0.38
S1PR1 P21453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30588948 1.00 QPCT (0.51) QPCTQPCTLIRAK4PRCPPRKCI
SCHEMBL29419338 0.72 PRCP (0.75) IRAK4PRCPCD44
SCHEMBL1403997 0.72 PRCP (0.75) IRAK4PRCPCD44
SCHEMBL14904920 0.72 PRCP (0.53) IRAK4PRCPCD44NMT1
SCHEMBL1012796 0.71 PRCP (0.55) IRAK4PRCPCD44NMT1S1PR1
SCHEMBL28937350 0.69 CD44 (0.41) CD44
SCHEMBL30174343 0.69 CD44 (0.41) CD44
SCHEMBL8634290 0.69 QPCT (0.68) QPCTQPCTLPRKCIKDM4ENPC1
SCHEMBL27824937 0.69 QPCT (0.64) QPCTQPCTLPRKCIALOX5APFEN1
SCHEMBL16154948 0.69 PRCP (0.49) IRAK4PRCPCD44NMT1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230272401-A1 COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF Genetic Intelligence, Inc 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272401-A1 COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF TARDBP, FUS, RBM17 QPCT 3307/4885QPCTL 1939/4885IRAK4 3089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.