Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429774 | 0.84 | CYP3A4 (0.49) | CYP3A4ALOX15POLBALDH1A1PDE4A | |
| SCHEMBL25367786 | 0.83 | CYP3A4 (0.67) | CYP3A4ALOX15POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL26060412 | 0.81 | CYP3A4 (0.68) | CYP3A4ALOX15POLBALDH1A1PDE4A | |
| Apiol SCHEMBL29410305 | 0.80 | CYP3A4 (1.00) | CYP3A4ALOX15POLBALDH1A1SMN1; SMN2 | |
| Apiol SCHEMBL497412 | 0.80 | CYP3A4 (1.00) | CYP3A4ALOX15POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13473554 | 0.80 | CYP3A4 (0.62) | CYP3A4ALOX15POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL26060390 | 0.79 | CYP3A4 (0.57) | CYP3A4ALOX15POLBALDH1A1MAPT | |
| SCHEMBL2563162 | 0.78 | CYP3A4 (0.60) | CYP3A4ALOX15HTR2AHTR2CHTR2B | |
| SCHEMBL26060414 | 0.77 | CYP3A4 (0.56) | CYP3A4ALOX15POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL29936543 | 0.77 | CYP3A4 (0.58) | CYP3A4ALOX15POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987566-B2 | Nerve damage preventing and nerve protecting compounds, preparation method thereof, pharmaceutical composition thereof, and their use | GENHEALTH PHARMA CO., LTD. (TW) | 2024-05-21 | — | — | US | claimed |
| EP-4230622-A1 | NERVE DAMAGE PREVENTING AND NERVE PROTECTING COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND THEIR USE | Genhealth Pharma Co., Ltd. (TW) | 2023-08-23 | — | — | EP | claimed |
| US-20230242501-A1 | NERVE DAMAGE PREVENTING AND NERVE PROTECTING COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND THEIR USE | GENHEALTH PHARMA CO., LTD. (TW) | 2023-08-03 | — | — | US | claimed |
| US-11987566-B2 | Nerve damage preventing and nerve protecting compounds, preparation method thereof, pharmaceutical composition thereof, and their use | GENHEALTH PHARMA CO., LTD. (TW) | 2024-05-21 | — | — | US | disclosed |
| EP-4230622-A1 | NERVE DAMAGE PREVENTING AND NERVE PROTECTING COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND THEIR USE | Genhealth Pharma Co., Ltd. (TW) | 2023-08-23 | — | — | EP | disclosed |
| US-20230242501-A1 | NERVE DAMAGE PREVENTING AND NERVE PROTECTING COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND THEIR USE | GENHEALTH PHARMA CO., LTD. (TW) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11987566-B2 | Nerve damage preventing and nerve protecting compounds, preparation method thereof, pharmaceutical composition thereof, and their use | NGF, GAP43, ACHE | CYP3A4 4276/4885ALOX15 118/4885POLB 1130/4885 |
| US-20230242501-A1 | NERVE DAMAGE PREVENTING AND NERVE PROTECTING COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND THEIR USE | NGF, GAP43, ACHE | CYP3A4 4276/4885ALOX15 118/4885POLB 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.