SCHEMBL25371634

SCHEMBL25371634

Cc1nc(C(F)(F)F)ccc1S(=O)(=O)N1CC2(CN(CC34COC(C)(C3)C4)C2)C1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TRPV4 Q9HBA0 1/20 0.39
▸ BRS3 P32247 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30567023 1.00 TRPV4 (0.39) TRPV4BRS3
SCHEMBL30567105 0.91 TRPV4 (0.38) TRPV4BRS3
SCHEMBL25370981 0.91 TRPV4 (0.38) TRPV4BRS3
SCHEMBL26065180 0.89 TRPV4 (0.38) TRPV4BRS3
SCHEMBL27346641 0.88 TRPV4 (0.41) TRPV4BRS3
SCHEMBL27346602 0.88 TRPV4 (0.41) TRPV4BRS3
SCHEMBL25371347 0.84 TRPV4 (0.41) TRPV4BRS3
SCHEMBL30719520 0.84 TRPV4 (0.41) TRPV4
SCHEMBL25372391 0.81 TRPV4 (0.40) TRPV4BRS3
SCHEMBL25372388 0.81 TRPV4 (0.40) TRPV4BRS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-29 — — US claimed
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 — — WO claimed
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-29 — — US disclosed
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP TRPV4 4535/4885BRS3 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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