SCHEMBL30719520

SCHEMBL30719520

Cc1nc(C(F)(F)F)ccc1S(=O)(=O)N1C[C@H]2CN(CC34COC(C)(C3)C4)C[C@]2(C)C1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TRPV4 Q9HBA0 6/20 0.41
▸ NR1H2 P55055 1/20 0.30
▸ NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27346641 0.87 TRPV4 (0.41) TRPV4NR1H2NR1H3
SCHEMBL27346602 0.87 TRPV4 (0.41) TRPV4NR1H2NR1H3
SCHEMBL30567023 0.84 TRPV4 (0.39) TRPV4
SCHEMBL25371634 0.84 TRPV4 (0.39) TRPV4
SCHEMBL26065180 0.84 TRPV4 (0.38) TRPV4
SCHEMBL30719473 0.78 TRPV4 (0.40) TRPV4NR1H2NR1H3
SCHEMBL27346583 0.78 TRPV4 (0.40) TRPV4NR1H2NR1H3
SCHEMBL30567105 0.76 TRPV4 (0.38) TRPV4
SCHEMBL25370981 0.76 TRPV4 (0.38) TRPV4
SCHEMBL26065199 0.75 TRPV4 (0.37) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554934-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 — — EP disclosed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO disclosed
Send feedback