SCHEMBL253728

SCHEMBL253728

CCCC(C)(CC)Oc1ccc(C(C)(C)c2ccc(OC(=O)c3cccc(C(=O)C(C)(C)CCC)c3)c(C)c2)cc1C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.34
VDR P11473 1/20 0.33
ESR1 P03372 6/20 0.32
MGLL Q99685 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
POLB P06746 1/20 0.31
ESR2 Q92731 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12352731 0.91 MRGPRX4 (0.35) MRGPRX4VDRESR1MGLLKDM4E
SCHEMBL14817471 0.91 MRGPRX4 (0.36) MRGPRX4VDRESR1MGLLKDM4E
SCHEMBL12352730 0.88 VDR (0.36) VDRESR1MGLLELANE
SCHEMBL12134166 0.88 MAPT (0.40) MRGPRX4VDRESR1MAPTMEN1
SCHEMBL3607757 0.81 MAPT (0.44) MRGPRX4VDRESR1MAPTMEN1
SCHEMBL12352799 0.81 VDR (0.35) VDRESR1MGLLMEN1KMT2A
SCHEMBL19431686 0.77 CREBBP (0.38) MRGPRX4VDRESR1KDM4EMAPT
SCHEMBL19805249 0.77 PPARA (0.34) SMN1; SMN2ELANE
SCHEMBL13497883 0.76 PPARG (0.37) VDRKMT2APOLB
SCHEMBL14034475 0.76 MRGPRX4 (0.30) MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 US disclosed