Bucetin

Bucetin

SCHEMBL25373

CCOc1ccc(NC(=O)CC(C)O)cc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.73
POLB P06746 1/20 0.71
SMN1; SMN2 Q16637 3/20 0.62
NPC1 O15118 1/20 0.62
HPGD P15428 1/20 0.62
RAB9A P51151 1/20 0.62
KMT2A Q03164 3/20 0.61
MEN1 O00255 1/20 0.61
LMNA P02545 1/20 0.61
CYP1A2 P05177 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
MAPT P10636 7/20 0.60
ALDH1A1 P00352 4/20 0.60
MAPK1 P28482 2/20 0.60
HTT P42858 1/20 0.60
KDM4E B2RXH2 1/20 0.60
TSHR P16473 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10294767 0.89 MAPT (0.73) GAAPOLBSMN1; SMN2NPC1HPGD
Bucetin SCHEMBL11647704 0.85 KMT2A (0.58) GAAPOLBSMN1; SMN2NPC1HPGD
Bufexamac SCHEMBL17710313 0.84 SMN1; SMN2 (0.67) GAAPOLBSMN1; SMN2NPC1HPGD
SCHEMBL9312707 0.83 POLB (1.00) POLBSMN1; SMN2NPC1HPGDRAB9A
SCHEMBL9978996 0.83 POLB (0.69) GAAPOLBSMN1; SMN2NPC1HPGD
SCHEMBL9979411 0.83 POLB (0.69) GAAPOLBSMN1; SMN2NPC1HPGD
SCHEMBL12445438 0.82 POLB (0.83) POLBSMN1; SMN2NPC1HPGDRAB9A
SCHEMBL26488 0.81 MAPT (0.65) GAAPOLBSMN1; SMN2NPC1HPGD
SCHEMBL8984662 0.81 LTA4H (0.70) POLBSMN1; SMN2NPC1HPGDRAB9A
SCHEMBL25086 0.80 POLB (0.80) POLBSMN1; SMN2NPC1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 EP claimed
US-20240165020-A1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-05-23 US claimed
EP-4360653-A2 LIQUISOFT CAPSULES Patheon Softgels Inc. (US) 2024-05-01 EP claimed
US-11872307-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2024-01-16 US claimed
EP-3682872-B1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-01-03 EP claimed
WO-2023205619-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-10-26 WO claimed
US-20230285282-A1 OCULAR IMPLANT CONTAINING AN ACTIVE INGREDIENT OCULAR THERAPEUTIX INC (US) 2023-09-14 US claimed
EP-4236943-A1 OCULAR IMPLANT CONTAINING AN ACTIVE AGENT Ocular Therapeutix, Inc. (US) 2023-09-06 EP claimed
EP-1252133-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-10-30 EP claimed
EP-1192129-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-04-03 EP claimed
EP-1169298-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-01-09 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
WO-2001012584-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2001-02-22 WO claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061541-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
WO-1998052616-A2 NONSTEROIDAL ANTIRHEUMATIC AGENTS OR THROMBOCYTE-AGGLUTINATION INHIBITORS TO IMPROVE REPRESENTATION OF VESSELS, LYMPH NODES AND BONE MARROW WITH PHARMACEUTICAL PREPARATIONS CONTAINING PARTICLES, VESICLES OF POLYMERS Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) 1998-11-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285282-A1 OCULAR IMPLANT CONTAINING AN ACTIVE INGREDIENT ERBB2, BTK, ERBB3 GAA 800/4885POLB 4423/4885SMN1; SMN2 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.