Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 1.00 |
| ▸ | HTR2C | P28335 | 10/20 | 0.56 |
| ▸ | HTR2B | P41595 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20970902 | 0.79 | HTR2A (0.65) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL26056042 | 0.78 | HTR2A (0.64) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL26056124 | 0.77 | HTR2A (0.62) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL27002138 | 0.76 | HTR2A (0.61) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL20970855 | 0.76 | HTR2A (0.61) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL27002059 | 0.75 | HTR2A (0.59) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL26055929 | 0.75 | HTR2A (0.68) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL26056043 | 0.74 | HTR2A (0.59) | HTR2AHTR2CHTR2BKDM4EATM | |
| SCHEMBL20970884 | 0.73 | HTR2A (0.58) | HTR2AHTR2CHTR2BKDM4EATM | |
| Hydrochloric Acid SCHEMBL25179886 | 0.73 | HTR2A (0.60) | HTR2AHTR2CHTR2BKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145566-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2025-05-08 | — | — | US | disclosed |
| WO-2023156453-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2023-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145566-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | PNMT, HTR7, HTR2C | HTR2A 7/4885HTR2C 3/4885HTR2B 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.