Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 12/20 | 0.63 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18075239 | 0.91 | PDE2A (0.68) | PDE2ALIPGSCN10A | |
| SCHEMBL30481795 | 0.91 | PDE2A (0.68) | PDE2ALIPGSCN10A | |
| SCHEMBL25375708 | 0.87 | PDE2A (0.47) | PDE2A | |
| SCHEMBL2268133 | 0.80 | PDE2A (0.54) | PDE2A | |
| SCHEMBL2268127 | 0.80 | PDE2A (0.54) | PDE2A | |
| SCHEMBL2268129 | 0.80 | PDE2A (0.54) | PDE2A | |
| SCHEMBL17025293 | 0.79 | PDE2A (0.61) | PDE2ALIPGSCN10ANOTUM | |
| SCHEMBL17025347 | 0.79 | PDE2A (0.61) | PDE2ALIPGSCN10ANOTUM | |
| SCHEMBL25374759 | 0.77 | PDE2A (0.50) | PDE2ASCN10A | |
| SCHEMBL18075371 | 0.77 | PDE2A (1.00) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |