Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374759 | 0.92 | PDE2A (0.50) | PDE2ANR1H2NR1H3 | |
| SCHEMBL25373699 | 0.87 | PDE2A (0.63) | PDE2A | |
| SCHEMBL30481795 | 0.78 | PDE2A (0.68) | PDE2A | |
| SCHEMBL18075239 | 0.78 | PDE2A (0.68) | PDE2A | |
| SCHEMBL26200269 | 0.78 | PDE2A (0.37) | PDE2A | |
| SCHEMBL25376231 | 0.77 | PDE2A (0.57) | PDE2ANR1H2NR1H3 | |
| SCHEMBL25373777 | 0.72 | SIGMAR1 (0.36) | PDE2A | |
| SCHEMBL2268127 | 0.71 | PDE2A (0.54) | PDE2A | |
| SCHEMBL2268129 | 0.71 | PDE2A (0.54) | PDE2A | |
| SCHEMBL2268133 | 0.71 | PDE2A (0.54) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |