Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2536448 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL2540311 | 0.80 | RAD52 (0.40) | — | |
| Hydrochloric Acid SCHEMBL6328982 | 0.79 | RAD52 (0.40) | — | |
| Hydrochloric Acid SCHEMBL2538139 | 0.79 | — | — | |
| SCHEMBL2127393 | 0.79 | RAD52 (0.41) | — | |
| Hydrochloric Acid SCHEMBL2537392 | 0.78 | HRH4 (0.30) | — | |
| SCHEMBL2129196 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2537577 | 0.77 | MAPT (0.36) | — | |
| Hydrochloric Acid SCHEMBL6331452 | 0.77 | MAPT (0.36) | — | |
| Hydrochloric Acid SCHEMBL1154193 | 0.76 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | claimed |
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | disclosed |