Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017132 | 0.81 | ALDH1A1 (0.73) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL24576210 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL13170238 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL30259908 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL885156 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL11123072 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL1244426 | 0.78 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL28333253 | 0.77 | HPGD (0.58) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL11120591 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EKMT2AGAA | |
| SCHEMBL11120594 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |