Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.55 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.52 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.52 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.52 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.52 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.52 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.52 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.52 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25372463 | 1.00 | ENPP2 (0.55) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL2833538 | 0.83 | CA1 (0.62) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL12413906 | 0.82 | ENPP2 (0.62) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL9858666 | 0.81 | ENPP2 (0.71) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL9510547 | 0.81 | ENPP2 (0.71) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL675018 | 0.81 | ENPP2 (0.71) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL12377319 | 0.81 | ENPP2 (0.58) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL9127420 | 0.80 | CA1 (0.62) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL11457343 | 0.80 | CA1 (0.62) | ENPP2DGAT2CA1CA2THRA | |
| SCHEMBL9127409 | 0.80 | THRA (0.62) | ENPP2DGAT2CA1CA2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238966-A1 | TETRAHYDRONAPHTHALENE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Guangzhou Henovcom Bioscience Co. Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |