Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374715 | 0.93 | TRPM8 (0.45) | GAATRPM8TSHRL3MBTL1KDM4E | |
| SCHEMBL30482162 | 0.93 | TRPM8 (0.45) | GAATRPM8TSHRL3MBTL1KDM4E | |
| SCHEMBL26216106 | 0.83 | TRPM8 (0.49) | TRPM8TSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30481998 | 0.80 | SCN8A (0.55) | SCN8AGAAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL25376566 | 0.79 | TRPM8 (0.52) | SCN8AGAATRPM8L3MBTL1KDM4E | |
| SCHEMBL25376461 | 0.79 | TRPM8 (0.44) | GAATRPM8TSHRL3MBTL1KDM4E | |
| SCHEMBL25374213 | 0.76 | SMN1; SMN2 (0.44) | TRPM8TSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25376236 | 0.76 | KDM4E (0.45) | SCN8AGAATRPM8TSHRL3MBTL1 | |
| 2-Pyridinecarboxaldehyde SCHEMBL25378590 | 0.73 | SCN8A (0.46) | SCN8AGAAL3MBTL1KDM4EMEN1 | |
| SCHEMBL25377449 | 0.72 | TRPM8 (0.57) | GAATRPM8TSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |