Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | YWHAG | P61981 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25373373 | 0.92 | KDM4E (0.51) | KDM4ETRPM8ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL25376566 | 0.90 | TRPM8 (0.52) | KDM4ETRPM8ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL25377547 | 0.87 | KDM4E (0.47) | KDM4ETRPM8ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL25375864 | 0.86 | SMN1; SMN2 (0.42) | KDM4ETRPM8ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL25378671 | 0.85 | ALDH1A1 (0.45) | KDM4ETRPM8ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL25377034 | 0.84 | L3MBTL1 (0.41) | KDM4ETRPM8ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL25377449 | 0.84 | TRPM8 (0.57) | KDM4ETRPM8ALDH1A1L3MBTL1TSHR | |
| SCHEMBL25375830 | 0.81 | TRPM8 (0.52) | TRPM8ALDH1A1NPSR1L3MBTL1TSHR | |
| SCHEMBL26216106 | 0.80 | TRPM8 (0.49) | KDM4ETRPM8ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL25376111 | 0.80 | TRPM8 (0.47) | KDM4ETRPM8ALDH1A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |