Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375678 | 1.00 | CTSK (0.38) | CTSKCA12CA14CA1CA7 | |
| SCHEMBL16326290 | 0.88 | CTSK (0.42) | CTSKCA12CA14CA1CA7 | |
| SCHEMBL18125237 | 0.85 | TDP1 (0.42) | CTSKCA12CA14CA1CA7 | |
| SCHEMBL18124759 | 0.85 | TDP1 (0.42) | CTSKCA12CA14CA1CA7 | |
| SCHEMBL19935593 | 0.85 | TDP1 (0.42) | CTSKCA12CA14CA1CA7 | |
| SCHEMBL90257 | 0.84 | CA12 (0.40) | CTSKCA12CA14CA1CA7 | |
| SCHEMBL25377703 | 0.82 | CTSK (0.39) | CTSKCA12CA14CA1CA7 | |
| SCHEMBL22005322 | 0.82 | CTSK (0.39) | CTSKCA12CA14CA1CA7 | |
| SCHEMBL25375641 | 0.81 | KMT2A (0.35) | CA1TDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL25375643 | 0.81 | KMT2A (0.35) | CA1TDP1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693527-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |