Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | PAM | P19021 | 2/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375643 | 1.00 | KMT2A (0.35) | KMT2AL3MBTL1MEN1MAPTATM | |
| SCHEMBL25375678 | 0.81 | CTSK (0.38) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL25375682 | 0.81 | CTSK (0.38) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL22832247 | 0.79 | MEN1 (0.38) | KMT2AL3MBTL1MEN1MAPTATM | |
| SCHEMBL18109605 | 0.79 | MEN1 (0.38) | KMT2AL3MBTL1MEN1MAPTATM | |
| SCHEMBL25375297 | 0.78 | FDPS (0.38) | KMT2AL3MBTL1MEN1MAPTATM | |
| SCHEMBL25375302 | 0.78 | FDPS (0.38) | KMT2AL3MBTL1MEN1MAPTATM | |
| SCHEMBL18131321 | 0.77 | ANO1 (0.33) | PKM | |
| SCHEMBL18109547 | 0.74 | MEN1 (0.44) | KMT2AL3MBTL1MEN1MAPTATM | |
| SCHEMBL18109544 | 0.74 | MEN1 (0.44) | KMT2AL3MBTL1MEN1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |