Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374361 | 0.92 | TRPM8 (0.59) | TRPM8MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL25376566 | 0.90 | TRPM8 (0.52) | TRPM8ALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL25376675 | 0.87 | TRPM8 (0.54) | TRPM8MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL25376560 | 0.85 | SMN1; SMN2 (0.44) | TRPM8MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL25377449 | 0.84 | TRPM8 (0.57) | TRPM8MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL25373541 | 0.83 | KDM5B (0.47) | TRPM8MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL25376236 | 0.81 | KDM4E (0.45) | TRPM8MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL25377248 | 0.81 | RECQL (0.51) | TRPM8MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL30482189 | 0.81 | RECQL (0.51) | TRPM8MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL25374376 | 0.79 | TRPM8 (0.52) | TRPM8MEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |