Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376345 | 0.93 | GRIN2B (0.41) | LMNAGRIN2BGRIN1MRGPRX4RAB9A | |
| SCHEMBL472513 | 0.78 | KMT2A (0.47) | FGFR4MAPKAPK2RAB9ANPC1HPGD | |
| SCHEMBL11984375 | 0.71 | BCHE (0.53) | LMNAGRIN2BGRIN1RAB9ANPC1 | |
| SCHEMBL34460869 | 0.68 | G6PC1 (0.58) | LMNARAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL13197243 | 0.68 | G6PC1 (0.58) | LMNARAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL14279422 | 0.67 | MEN1 (0.52) | LMNARAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL4414108 | 0.67 | KIF11 (0.47) | — | |
| SCHEMBL31739263 | 0.67 | KDM1A (0.49) | MRGPRX4RAB9ASMONPC1HPGD | |
| SCHEMBL4813453 | 0.67 | MEN1 (0.52) | LMNARAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL16860883 | 0.65 | KMT2A (0.43) | FGFR4MAPKAPK2RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |