Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | IL6 | P05231 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800327 | 0.87 | EPHX2 (0.46) | EPHX2PPARGKDM4EALDH1A1SCN8A | |
| SCHEMBL30482017 | 0.87 | EPHX2 (0.46) | EPHX2PPARGKDM4EALDH1A1SCN8A | |
| SCHEMBL28170854 | 0.77 | SCN8A (0.52) | EPHX2PPARGKDM4EALDH1A1HTT | |
| SCHEMBL67207 | 0.76 | NFKB1 (0.57) | ALDH1A1TDP1LMNANFKB1TNF | |
| SCHEMBL29417728 | 0.76 | NFKB1 (0.57) | ALDH1A1TDP1LMNANFKB1TNF | |
| Alcohol SCHEMBL27946760 | 0.74 | NFKB1 (0.51) | TDP1LMNASMN1; SMN2NFKB1TNF | |
| SCHEMBL18893127 | 0.73 | EPHX2 (0.44) | EPHX2PPARGSCN8APOLB | |
| SCHEMBL7592052 | 0.72 | NFKB1 (0.41) | ALDH1A1HTTTDP1LMNASMN1; SMN2 | |
| SCHEMBL8059946 | 0.72 | IDO1 (0.44) | KDM4EALDH1A1TDP1LMNANFKB1 | |
| SCHEMBL13208315 | 0.72 | BCHE (0.45) | ALDH1A1TDP1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |