SCHEMBL67207

SCHEMBL67207

O=Cc1ccccc1C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.57
MEN1 O00255 1/20 0.55
LMNA P02545 1/20 0.55
THRB P10828 1/20 0.55
BLM P54132 1/20 0.55
KMT2A Q03164 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
TNF P01375 1/20 0.50
IL6 P05231 1/20 0.50
MAOB P27338 4/20 0.47
GRIN2D O15399 2/20 0.47
GRIN3B O60391 2/20 0.47
GRIN1 Q05586 2/20 0.47
GRIN2A Q12879 2/20 0.47
GRIN2B Q13224 2/20 0.47
GRIN2C Q14957 2/20 0.47
GRIN3A Q8TCU5 2/20 0.47
P4HB P07237 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29417728 1.00 NFKB1 (0.57) NFKB1MEN1LMNATHRBBLM
Trifluoroacetic Acid SCHEMBL1922217 0.88 NFKB1 (0.56) NFKB1MEN1LMNATHRBBLM
SCHEMBL8698782 0.88 ALDH1A1 (0.67) NFKB1MEN1LMNATHRBBLM
Alcohol SCHEMBL27946760 0.88 NFKB1 (0.51) NFKB1MEN1LMNATHRBBLM
SCHEMBL7527284 0.88 NFKB1 (0.47) NFKB1MEN1LMNATHRBBLM
SCHEMBL28275325 0.85 NFKB1 (0.45) NFKB1MEN1LMNATHRBBLM
SCHEMBL4846671 0.83 MEN1 (0.46) NFKB1MEN1LMNATHRBBLM
2-Nitrobenzaldehyde SCHEMBL17046828 0.82 ERN1 (0.50) NFKB1MEN1LMNAKMT2ATNF
SCHEMBL6853771 0.82 NFKB1 (0.44) NFKB1MEN1LMNATHRBBLM
SCHEMBL17103316 0.82 LMNA (0.50) NFKB1MEN1LMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3081 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120148634-A Radix ophiopogonis origin identification method based on circular dichroism analysis 宁波大学 2025-06-13 CN claimed
WO-2025101667-A1 DIFFUSION BARRIERS TO REDUCE QUEUE-TIME EFFECTS IN EUV LITHOGRAPHY LAM RESEARCH CORPORATION (US) 2025-05-15 WO claimed
WO-2025099451-A1 NEW COMPOUNDS AND METHODS Transition Bio Limited (GB) 2025-05-15 WO claimed
CN-119119116-A Rhein phosphoryl derivative and synthetic method and application thereof 甘肃中医药大学 2024-12-13 CN claimed
CN-117143598-B High-entropy carbon quantum dot nanomaterial and preparation method and application thereof 中南大学 2024-11-08 CN claimed
CN-118496173-A Fluorine-containing 1,3, 4-oxadiazole-amide hybrid, and preparation method and application thereof 上海理工大学 2024-08-16 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118384915-A High-efficiency furfural oxidation active electrocatalyst based on electron beam irradiation and preparation method and application thereof 上海大学 2024-07-26 CN claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
EP-0396987-A2 Nuclear fluorinated trifluoromethylbenzaldehydes BAYER AG (DE) 1990-11-14 EP claimed
US-4808746-A Preparation of trifluoromethylbenzonitrile from trifluoromethylbenzaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 1989-02-28 US claimed
EP-0077853-B1 NOVEL TRIFLUOROMETHYL BENZAL CHLORIDES AND PROCESS FOR THE PREPARATION THEREOF OCCIDENTAL CHEMICAL CORPORATION (US) 1985-03-13 EP claimed
EP-0077853-A1 Novel trifluoromethyl benzal chlorides and process for the preparation thereof OCCIDENTAL CHEMICAL CORPORATION (US) 1983-05-04 EP claimed
US-4367348-A Novel trifluoromethyl benzal chlorides and process for the preparation thereof OCCIDENTAL CHEMICAL CORPORATION (US) 1983-01-04 US claimed
US-4301167-A ANTIINFLAMMATORY AGENTS, ANALGESICS INSTITUT MERIEUX (FR) 1981-11-17 US claimed
EP-0001947-B1 2-AMINO-THIAZOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL PREPARATIONS INSTITUT MERIEUX (FR) 1981-10-14 EP claimed
EP-0001947-A1 2-Amino-thiazoline derivatives, their preparation and their use in pharmaceutical preparations INSTITUT MERIEUX (FR) 1979-05-16 EP claimed
WO-1979000231-A1 NEW THIAZOLINE DERIVATIVES AND THEIR APPLICATION AS MEDICINE MERIEUX INST (FR) 1979-05-03 WO claimed
US-3951993-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed