Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376166 | 1.00 | LTA4H (0.51) | LTA4HKDM1ADRD1DRD3DRD2 | |
| SCHEMBL25380103 | 0.89 | DRD1 (0.54) | LTA4HKDM1ADRD1DRD3DRD2 | |
| SCHEMBL25377523 | 0.89 | DRD1 (0.54) | LTA4HKDM1ADRD1DRD3DRD2 | |
| SCHEMBL25379894 | 0.86 | KDM4E (0.58) | LTA4HKDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL25379898 | 0.86 | KDM4E (0.58) | LTA4HKDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL25381009 | 0.86 | KDM4E (0.58) | LTA4HKDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL25376716 | 0.86 | KDM4E (0.58) | LTA4HKDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL7400266 | 0.83 | GAA (0.62) | LTA4HKDM1ALIPEKDM4EALDH1A1 | |
| SCHEMBL25379791 | 0.83 | KDM1A (0.55) | LTA4HKDM1ADRD1DRD3DRD2 | |
| SCHEMBL25378487 | 0.83 | KDM1A (0.55) | LTA4HKDM1ADRD1DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482832-A1 | 5-[7-(3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBONYL)-1,2,3,4 TETRAHYDROISOQUINOLIN-6-Y L]-1H-PYRROLE-3-CARBOXAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | Les Laboratoires Servier (FR) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023161317-A1 | 5-[7-(3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBONYL)-1,2,3,4 TETRAHYDROISOQUINOLIN-6-Y L]-1H-PYRROLE-3-CARBOXAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | LES LABORATOIRES SERVIER (FR) | 2023-08-31 | — | — | WO | disclosed |