Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251563 | 1.00 | MAPK1 (0.40) | MAPK1HTTSMN1; SMN2NR3C1PIK3CD | |
| SCHEMBL617678 | 0.88 | HTT (0.41) | MAPK1HTTSMN1; SMN2NR3C1SUCNR1 | |
| SCHEMBL253866 | 0.88 | SUCNR1 (0.38) | MAPK1SUCNR1KLKB1 | |
| SCHEMBL253868 | 0.84 | MAPK1 (0.32) | MAPK1HTTSMN1; SMN2KLKB1 | |
| SCHEMBL253867 | 0.84 | MAPK1 (0.32) | MAPK1HTTSMN1; SMN2KLKB1 | |
| SCHEMBL10232885 | 0.81 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2NR3C1SUCNR1HCRTR1 | |
| SCHEMBL619738 | 0.81 | HCRTR1 (0.52) | HTTSMN1; SMN2NR3C1SUCNR1HCRTR1 | |
| SCHEMBL616887 | 0.80 | CSF1R (0.47) | HTTSMN1; SMN2HDAC6 | |
| SCHEMBL620104 | 0.79 | NR3C1 (0.54) | HTTSMN1; SMN2NR3C1SUCNR1POLB | |
| SCHEMBL619617 | 0.78 | HTT (0.45) | HTTSMN1; SMN2NR3C1SUCNR1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | claimed |