Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620104 | 0.90 | NR3C1 (0.54) | SMN1; SMN2HTTSUCNR1NR3C1POLB | |
| SCHEMBL619617 | 0.88 | HTT (0.45) | SMN1; SMN2HTTSUCNR1NR3C1HDAC6 | |
| SCHEMBL620473 | 0.88 | PTGDR2 (0.47) | SMN1; SMN2HTTSUCNR1NR3C1HDAC6 | |
| SCHEMBL20244979 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTHCRTR1HCRTR2POLB | |
| SCHEMBL617600 | 0.86 | HTT (0.54) | SMN1; SMN2HTTSUCNR1HDAC6HPGD | |
| SCHEMBL619554 | 0.86 | HTT (0.43) | SMN1; SMN2HTTSUCNR1NR3C1HDAC6 | |
| SCHEMBL617401 | 0.86 | HTT (0.46) | SMN1; SMN2HTTSUCNR1NR3C1HDAC6 | |
| SCHEMBL619738 | 0.86 | HCRTR1 (0.52) | SMN1; SMN2HTTSUCNR1NR3C1HCRTR1 | |
| SCHEMBL247884 | 0.84 | LMNA (0.52) | SMN1; SMN2HTTHPGDLMNA | |
| SCHEMBL619784 | 0.84 | TRPV1 (0.53) | SMN1; SMN2HTTSUCNR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415333-B2 | Bronchodilating diazaheteroaryls | RESPIRATORIOUS AB (SE) | 2013-04-09 | — | — | US | disclosed |
| US-20120040942-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040942-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | CHRM3, ADRB1, ADRB3 | SMN1; SMN2 4137/4885HTT 4219/4885SUCNR1 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.