Hypoxanthine

Hypoxanthine

SCHEMBL25381

O=c1[nH]cnc2nc[nH]c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 1.00
PNP P00491 1/20 0.57
PI4KA P42356 2/20 0.48
PI4K2B Q8TCG2 2/20 0.48
PI4K2A Q9BTU6 2/20 0.48
PI4KB Q9UBF8 2/20 0.48
LMNA P02545 2/20 0.48
XDH P47989 2/20 0.48
LRRK2 Q5S007 2/20 0.48
DRD3 P35462 1/20 0.48
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
GRIA4 P48058 1/20 0.47
PDPK1 O15530 3/20 0.47
GDA Q9Y2T3 2/20 0.46
ACHE P22303 1/20 0.46
G6PD P11413 1/20 0.46
TSHR P16473 1/20 0.45
ADORA2A P29274 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hypoxanthine SCHEMBL7037918 1.00 ALDH1A1 (1.00) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL30096461 1.00 ALDH1A1 (1.00) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL30703487 0.97 ALDH1A1 (0.95) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL28774651 0.97 ALDH1A1 (0.95) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL29846560 0.97 ALDH1A1 (0.95) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL122843 0.97 ALDH1A1 (0.95) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL560392 0.97 ALDH1A1 (0.95) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL7168422 0.97 ALDH1A1 (0.95) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL2639254 0.97 ALDH1A1 (0.95) ALDH1A1PNPPI4KAPI4K2BPI4K2A
Hypoxanthine SCHEMBL28386541 0.97 ALDH1A1 (0.95) ALDH1A1PNPPI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 149035 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
EP-4747386-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE AGENTS AND USES THEREOF Bisirna Therapeutics Pte. Ltd. (SG) 2026-05-27 EP claimed
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122081155-A Pediococcus acidilactici TC-4 capable of degrading nucleoside, purine and uric acid simultaneously and application thereof 2026-05-26 CN claimed
CN-122080194-A Anti-H5 subtype avian influenza virus hemagglutinin protein monoclonal antibody 1F8 and application thereof 2026-05-26 CN claimed
CN-122095092-A Inhibitor for inhibiting inhibin Beta E gene expression and application thereof 2026-05-26 CN claimed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 US claimed
WO-1983002616-A1 COMPOSITION AND METHOD FOR FORMING A5'p5'pn3'p (AppNp) INNOVAX LAB LTD (US) 1983-08-04 WO claimed
EP-0016845-B1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1983-07-13 EP claimed
EP-0076647-A2 Culture media for cells originating from the immune system HANA Biologics Incorporated (US) 1983-04-13 EP claimed
US-4371613-A TRANSARABINOSYLATION USING AN ENZYME FROM BACTERIA, AN ARABINOSE DONOR AND A PURINE SOURCE AJINOMOTO COMPANY INCORPORATED (JP) 1983-02-01 US claimed
US-4341868-A PEROXIDATION; COLORIMETRY; QUANTITAVE ANALYSIS; ONE-STEP; ENTEROBACTER KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-07-27 US claimed
US-4266048-A Synthesis of analogs of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1981-05-05 US claimed
EP-0016845-A1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1980-10-15 EP claimed
US-4218535-A Determination of enzyme substrate concentration BECKMAN INSTRUMENTS, INC. (US) 1980-08-19 US claimed
US-4108804-A Process for preparation of chromatography solid supports comprising a nucleic acid base-epoxy group containing porous gel SEITA TORU 1978-08-22 US claimed
US-3939089-A PEROXYSULFATE TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-02-17 US claimed