SCHEMBL25383151

SCHEMBL25383151

[O]Cc1cc(I)ccc1Br

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.31
ERN1 O75460 1/20 0.30
HSP90AA1 P07900 1/20 0.30
TLR9 Q9NR96 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15430107 0.84 GABRA1 (0.39)
SCHEMBL15271148 0.81 IDO1 (0.31) IDO1
SCHEMBL30594531 0.81 IDO1 (0.31) IDO1
SCHEMBL31318281 0.79 SLC6A4 (0.40)
SCHEMBL1714214 0.79 IDO1 (0.33) IDO1
SCHEMBL1713834 0.79 SLC6A4 (0.40)
SCHEMBL27177080 0.79 TAAR1 (0.35) IDO1
SCHEMBL28903778 0.79 SLC6A4 (0.30)
SCHEMBL26586497 0.79
SCHEMBL1047304 0.78 HSP90AA1 (0.46) HSP90AA1TLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023160672-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LHOTSE BIO , INC. (US) 2023-08-31 WO disclosed