SCHEMBL1713834

SCHEMBL1713834

OCc1cc(I)ccc1Br

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 4/20 0.40
SLC6A2 P23975 3/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31318281 1.00 SLC6A4 (0.40) SLC6A4SLC6A2PTGDR2
SCHEMBL29010273 0.82 SLC6A4 (0.37) SLC6A4SLC6A2PTGDR2
SCHEMBL28903778 0.82 SLC6A4 (0.30) SLC6A4
SCHEMBL25383151 0.79 IDO1 (0.31)
SCHEMBL15271148 0.79 IDO1 (0.31)
SCHEMBL30594531 0.79 IDO1 (0.31)
SCHEMBL6156516 0.78 SLC6A4 (0.43) SLC6A4SLC6A2
SCHEMBL15430107 0.77 GABRA1 (0.39) SLC6A4
SCHEMBL1714214 0.77 IDO1 (0.33)
SCHEMBL27177080 0.77 TAAR1 (0.35) SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113233957-B Preparation method of 2-bromo-5-iodo-benzyl alcohol 成都工业学院 2023-05-02 CN claimed
CN-113233957-A Preparation method of 2-bromo-5-iodo-benzyl alcohol 成都工业学院 2021-08-10 CN claimed
CN-103965020-B Prepare the method for 5-iodo-2-bromobenzyl alcohol QIDONG DONGYUE PHARMACY CO., LTD. (CN) 2015-09-09 CN claimed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
EP-4482579-B1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LHOTSE BIO INC (US) 2026-02-18 EP disclosed
WO-2025245178-A1 PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS INNOVO THERAPEUTICS, INC. (US) 2025-11-27 WO disclosed
US-12428375-B2 Compounds and compositions for treating conditions associated with LPA receptor activity LHOTSE BIO, INC. (US) 2025-09-30 US disclosed
US-20250268929-A1 TREATMENT OF METABOLIC DISORDERS IN EQUINE ANIMALS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-08-28 US disclosed
EP-3847224-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2025-08-06 EP disclosed
US-20240400584-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. 2024-12-05 US disclosed
US-20240376054-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LHOTSE BIO, INC. 2024-11-14 US disclosed
EP-1989191-A1 GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE Boehringer Ingelheim International GmbH (DE) 2008-11-12 EP disclosed
US-20080058379-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-03-06 US disclosed
US-20080058379-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-03-06 US disclosed
US-20080058379-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-03-06 US disclosed
WO-2007128749-A1 GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-11-15 WO disclosed
US-20070259821-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-11-08 US disclosed
US-20070259821-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-11-08 US disclosed
US-20070259821-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-11-08 US disclosed
WO-2007093610-A1 GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400584-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING RBM17, SNRPA, SNRPA1 SLC6A4 3351/4885SLC6A2 4098/4885PTGDR2 3937/4885
US-20250268929-A1 TREATMENT OF METABOLIC DISORDERS IN EQUINE ANIMALS SLC5A2, SLC5A1, SLC2A8 SLC6A4 36/4885SLC6A2 22/4885PTGDR2 1709/4885
US-20080058379-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture UGGT1, GALE, UGT1A4 SLC6A4 363/4885SLC6A2 574/4885PTGDR2 4319/4885
US-20240376054-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LPAR2, LPAR1, LPAR6 SLC6A4 3623/4885SLC6A2 2937/4885PTGDR2 324/4885
US-20070259821-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture UGGT1, UGT1A4, SLC5A1 SLC6A4 337/4885SLC6A2 565/4885PTGDR2 4204/4885
US-12428375-B2 Compounds and compositions for treating conditions associated with LPA receptor activity LPAR2, LPAR1, LPAR6 SLC6A4 3623/4885SLC6A2 2937/4885PTGDR2 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.