Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 14/20 | 1.00 |
| ▸ | PMM2 | O15305 | 13/20 | 1.00 |
| ▸ | G6PD | P11413 | 5/20 | 0.76 |
| ▸ | MIF | P14174 | 3/20 | 0.71 |
| ▸ | PHOSPHO1 | Q8TCT1 | 12/20 | 0.69 |
| ▸ | APOBEC3G | Q9HC16 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.69 |
| ▸ | CASP3 | P42574 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373420 | 0.88 | G6PD (0.80) | MPIPMM2G6PDMIFPHOSPHO1 | |
| SCHEMBL17502105 | 0.87 | MPI (0.76) | MPIPMM2G6PDMIFPHOSPHO1 | |
| SCHEMBL1897990 | 0.86 | G6PD (1.00) | MPIPMM2G6PDMIFPHOSPHO1 | |
| SCHEMBL8373532 | 0.84 | MIF (0.74) | MPIPMM2G6PDMIFPHOSPHO1 | |
| SCHEMBL8372534 | 0.84 | MPI (0.72) | MPIPMM2G6PDMIFPHOSPHO1 | |
| SCHEMBL22092498 | 0.83 | MIF (1.00) | MPIPMM2G6PDMIFPHOSPHO1 | |
| SCHEMBL1898397 | 0.82 | MPI (1.00) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL30562926 | 0.82 | MPI (1.00) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL2413025 | 0.82 | MPI (1.00) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL8370795 | 0.81 | G6PD (0.69) | MPIPMM2G6PDPHOSPHO1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |
| US-20110257233-A1 | BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110257233-A1 | BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110257233-A1 | BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2011116355-A2 | BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-22 | — | — | WO | disclosed |
| EP-0644243-B1 | Anti-fouling compositions or fouling control of harmful aquatic oranisms | SUMITOMO CHEMICAL CO (JP) | 1999-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257233-A1 | BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE | MPI, PMM2, GPI | MPI 1/4885PMM2 2/4885G6PD 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.