SCHEMBL1898397

SCHEMBL1898397

O=c1c2ccccc2sn1-c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPI P34949 15/20 1.00
PMM2 O15305 12/20 1.00
PHOSPHO1 Q8TCT1 12/20 1.00
G6PD P11413 6/20 1.00
APOBEC3G Q9HC16 5/20 1.00
KDM4E B2RXH2 2/20 1.00
ALDH1A1 P00352 2/20 1.00
MAPT P10636 2/20 1.00
PKM P14618 2/20 1.00
HPGD P15428 2/20 1.00
ALOX12 P18054 2/20 1.00
CASP3 P42574 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
HSP90AA1 P07900 1/20 1.00
RAB9A P51151 2/20 0.74
NPC1 O15118 1/20 0.74
TP53 P04637 1/20 0.74
SMN1; SMN2 Q16637 1/20 0.74
KDM5B Q9UGL1 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30562926 1.00 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL30738364 0.98 MPI (0.96) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL29910151 0.85 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL21033372 0.85 MPI (0.74) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL2537846 0.85 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL2443755 0.85 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL1894451 0.85 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL18913003 0.85 MPI (0.74) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL1900552 0.85 MPI (0.74) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL8373516 0.85 MPI (0.74) MPIPMM2PHOSPHO1G6PDAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496231-B Preparation method of N-phenyl-2, 3-dihydro-4H-1, 3-benzothiazine-4-ketone 常州大学 2025-04-04 CN claimed
CN-116496231-A Preparation method of N-phenyl-2, 3-dihydro-4H-1, 3-benzothiazine-4-ketone 常州大学 2023-07-28 CN claimed
US-11707453-B2 Treatment of unipolar depressive disorder OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-07-25 US claimed
EP-3448379-B1 TREATMENT OF IMPULSIVITY-RELATED DISORDERS UNIV OXFORD INNOVATION LTD (GB) 2023-06-28 EP claimed
US-20210060051-A1 COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS EMORY UNIVERSITY 2021-03-04 US claimed
US-20210000803-A1 TREATMENT OF UNIPOLAR DEPRESSIVE DISORDER OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2021-01-07 US claimed
EP-3732180-A1 COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS Emory University (US) 2020-11-04 EP claimed
US-10653680-B2 Treatment of impulsivity-related disorders OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2020-05-19 US claimed
US-20190111029-A1 TREATMENT OF IMPULSIVITY-RELATED DISORDERS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2019-04-18 US claimed
EP-2673048-A2 TREATMENT OF BIPOLAR DISORDER Isis Innovation Limited (GB) 2013-12-18 EP claimed
WO-2012107735-A2 TREATMENT OF BIPOLAR DISORDER ISIS INNOVATION LTD (GB) 2012-08-16 WO claimed
WO-2011062864-A2 INHIBITORS OF NOX ENZYMES AND METHODS OF USE THEREOF EMORY UNIVERSITY (US) 2011-05-26 WO claimed
US-6001863-A USEFUL AS ANTIVIRAL, ANTIINFLAMMATORY AND ANTIATHEROSCLEROSIS AGENT; ADMINISTERING TO THE PATIENT IN NEED OF ZINC EJECTION FROM NUCLEOCAPSID PROTEIN WARNER-LAMBERT COMPANY (US) 1999-12-14 US claimed
EP-0644243-B1 Anti-fouling compositions or fouling control of harmful aquatic oranisms SUMITOMO CHEMICAL CO (JP) 1999-01-27 EP claimed
US-5507862-A PROTECTIVE COATINGS CONTAINING SUBSTITUTED N-PHENYLISOTHIAZOLONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-16 US claimed
EP-0644243-A2 Anti-fouling compositions or fouling control of harmful aquatic oranisms SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-22 EP claimed
JP-7233014-A None JP disclosed
JP-8188506-A None JP disclosed
EP-0644243-A2 Anti-fouling compositions or fouling control of harmful aquatic oranisms SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-22 EP disclosed
EP-0644243-A2 Anti-fouling compositions or fouling control of harmful aquatic oranisms SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707453-B2 Treatment of unipolar depressive disorder SLC6A2, CHRM1, SLC1A2 MPI 1405/4885PMM2 3009/4885PHOSPHO1 1285/4885
US-20210060051-A1 COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS NOX1, NOX3, NOX4 MPI 321/4885PMM2 2645/4885PHOSPHO1 2868/4885
US-20210000803-A1 TREATMENT OF UNIPOLAR DEPRESSIVE DISORDER SLC6A2, CHRM1, SLC1A2 MPI 1405/4885PMM2 3009/4885PHOSPHO1 1285/4885
US-20190111029-A1 TREATMENT OF IMPULSIVITY-RELATED DISORDERS DRD2, DRD3, DRD1 MPI 2619/4885PMM2 3665/4885PHOSPHO1 3858/4885
US-10653680-B2 Treatment of impulsivity-related disorders DRD2, DRD3, DRD1 MPI 2619/4885PMM2 3665/4885PHOSPHO1 3858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.