Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377802 | 0.88 | KDM4E (0.50) | SMN1; SMN2KDM4EMAPTHSD17B10L3MBTL1 | |
| SCHEMBL25386128 | 0.88 | PPARG (0.48) | PPARGSMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL25386200 | 0.88 | ALDH1A1 (0.52) | PPARGSMN1; SMN2KDM4EMAPTL3MBTL1 | |
| SCHEMBL13387961 | 0.86 | POLB (0.50) | SMN1; SMN2KDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL12093646 | 0.83 | PPARG (0.48) | PPARGSMN1; SMN2KDM4EMAPTHSD17B10 | |
| SCHEMBL1399960 | 0.83 | HSD17B10 (0.63) | SMN1; SMN2KDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL13469239 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL21455751 | 0.82 | ALDH1A1 (0.53) | PPARGKDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL21437412 | 0.82 | POLB (0.59) | PPARGPOLBHSD17B10NPC1RAB9A | |
| SCHEMBL13742193 | 0.82 | PPARG (0.47) | PPARGSMN1; SMN2KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165591-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUTHER PHARMATECH (SHANGHAI) CO., LTD. (CN) | 2023-09-07 | — | — | WO | disclosed |