SCHEMBL25387262

SCHEMBL25387262

C=CC(=O)NN[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.48
NOS2 P35228 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NAALAD2 Q9Y3Q0 2/20 0.46
MMP2 P08253 4/20 0.44
MMP9 P14780 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 1/20 0.44
ADAMTS4 O75173 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
FOLH1 Q04609 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25387266 1.00 MME (0.48) MMENOS2NPSR1NAALAD2MMP2
SCHEMBL29214532 0.84 MME (0.58) MMENOS2NPSR1NAALAD2L3MBTL1
SCHEMBL1135185 0.84 MME (0.58) MMENOS2NPSR1NAALAD2L3MBTL1
SCHEMBL1135183 0.84 MME (0.58) MMENOS2NPSR1NAALAD2L3MBTL1
SCHEMBL4432859 0.83 MMP8 (0.49) L3MBTL1ALDH1A1
SCHEMBL157547 0.81 MME (0.61) MMENPSR1NAALAD2MMP2MMP9
SCHEMBL29064035 0.79 MME (0.51) MMENPSR1NAALAD2L3MBTL1CYP1A2
SCHEMBL11262817 0.79 MME (0.51) MMENPSR1NAALAD2L3MBTL1CYP1A2
SCHEMBL27850341 0.79 MME (0.51) MMENPSR1NAALAD2L3MBTL1CYP1A2
SCHEMBL5389540 0.78 MME (0.57) MMENPSR1NAALAD2MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4490202-A1 CYCLOPEPTIBODIES AND USES THEREOF University of Rochester (US) 2025-01-15 EP claimed
CN-118892583-A High-wet tissue adhesion anti-swelling conductive hydrogel and preparation method thereof 西安交通大学 2024-11-05 CN claimed
WO-2023173084-A9 CYCLOPEPTIBODIES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2023-12-14 WO claimed
WO-2023173084-A1 CYCLOPEPTIBODIES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2023-09-14 WO claimed
CN-109206617-B Method for resolving racemic compound by fractional crystallization 北京大学 2020-04-24 CN claimed
CN-118892583-B High-wet tissue adhesion anti-swelling conductive hydrogel and preparation method thereof 西安交通大学 2026-05-12 CN disclosed
CN-118892583-A High-wet tissue adhesion anti-swelling conductive hydrogel and preparation method thereof 西安交通大学 2024-11-05 CN disclosed
WO-2023173084-A9 CYCLOPEPTIBODIES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2023-12-14 WO disclosed
WO-2023173084-A1 CYCLOPEPTIBODIES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2023-09-14 WO disclosed
CN-109206617-B Method for resolving racemic compound by fractional crystallization 北京大学 2020-04-24 CN disclosed