SCHEMBL1135183

SCHEMBL1135183

C=CC(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.58
NPSR1 Q6W5P4 1/20 0.56
NOS2 P35228 1/20 0.56
NAALAD2 Q9Y3Q0 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
ACE P12821 2/20 0.52
CPA1 P15085 2/20 0.52
ACE2 Q9BYF1 2/20 0.52
FPR2 P25090 5/20 0.51
PTPN1 P18031 1/20 0.51
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1135185 1.00 MME (0.58) MMENPSR1NOS2NAALAD2L3MBTL1
SCHEMBL29214532 1.00 MME (0.58) MMENPSR1NOS2NAALAD2L3MBTL1
SCHEMBL8765449 0.87 MMP2 (0.53) NOS2
SCHEMBL30511891 0.87 FOLH1 (0.57) MMENOS2NAALAD2L3MBTL1ACE
SCHEMBL1097344 0.87 FOLH1 (0.57) MMENOS2NAALAD2L3MBTL1ACE
SCHEMBL23489850 0.87 MMP2 (0.53) NOS2
SCHEMBL8373360 0.87 HPGDS (0.50)
SCHEMBL8373361 0.87 HPGDS (0.50)
SCHEMBL1097343 0.87 FOLH1 (0.57) MMENOS2NAALAD2L3MBTL1ACE
SCHEMBL17244060 0.87 MME (0.58) MMENPSR1NAALAD2L3MBTL1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118085168-A Preparation method and application of acryloylphenylalanine-N-vinyl pyrrolidone chiral hydrogel film 常州大学 2024-05-28 CN claimed
CN-118063690-A Acrylophenylalanine-acrylic ester chiral copolymerization macromolecule hydrogel and preparation method and application thereof 常州大学 2024-05-24 CN claimed
CN-115612014-B Biological tissue adhesive capable of being adhered when meeting water and preparation method thereof 西安交通大学 2024-02-13 CN claimed
CN-114306376-B Peanut allergen protein affinity adsorption reagent, preparation method and application thereof 北京理工大学 2023-08-08 CN claimed
CN-115612014-A Biological tissue adhesive capable of adhering immediately when meeting water and preparation method thereof 西安交通大学 2023-01-17 CN claimed
CN-115414520-A Self-gel styptic powder and preparation method and application thereof 西安交通大学 2022-12-02 CN claimed
CN-114149544-B Adhesive photonic crystal hydrogel sensor and preparation method and application thereof 北京理工大学 2022-11-04 CN claimed
CN-114149544-A Adhesive photonic crystal hydrogel sensor and preparation method and application thereof 北京理工大学 2022-03-08 CN claimed
CN-112142911-A High-toughness hydrogel based on amino acid acrylamide derivative and preparation method thereof 西安交通大学 2020-12-29 CN claimed
US-20190119415-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2019-04-25 US claimed
CN-103897106-B Method for improving grafting rate of polyolefin grafted unsaturated carboxylic acid monomer 哈尔滨工程大学 2016-06-29 CN claimed
CN-105174747-A Glass fiber with amino acid grafted to surface and preparation method UNIV TIANJIN POLYTECHNIC 2015-12-23 CN claimed
US-20140183136-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2014-07-03 US claimed
CN-103897106-A Method for improving grafting rate of polyolefin grafted unsaturated carboxylic acid monomer UNIV HARBIN ENG 2014-07-02 CN claimed
EP-2152405-B1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2012-10-17 EP claimed
CN-102432778-A Preparation method of self-supporting molecularly imprinted polymer membrane UNIV SHANGHAI 2012-05-02 CN claimed
CN-102268119-A Preparation method of molecular imprinted polymer for detecting lung cancer tumor markers 2011-12-07 CN claimed
US-20100181254-A1 GRAFT COPOLYMER FOR CATION- EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-07-22 US claimed
EP-2152405-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY Merck Patent GmbH (DE) 2010-02-17 EP claimed
WO-2008145270-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2008-12-04 WO claimed