Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575766 | 1.00 | DPP4 (0.43) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL30575737 | 0.89 | DPP4 (0.50) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL11377134 | 0.89 | DPP4 (0.50) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL31609504 | 0.83 | DPP4 (0.45) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL11375452 | 0.81 | DPP4 (0.46) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL25386161 | 0.81 | LCK (0.49) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL25387590 | 0.80 | HSD17B2 (0.51) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL31609590 | 0.80 | DPP4 (0.41) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL31609523 | 0.79 | DPP4 (0.42) | DPP4GAAALDH1A1KMT2AMAPT | |
| SCHEMBL13469397 | 0.78 | KMT2A (0.53) | DPP4GAAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165591-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUTHER PHARMATECH (SHANGHAI) CO., LTD. (CN) | 2023-09-07 | — | — | WO | disclosed |