SCHEMBL31609523

SCHEMBL31609523

CCOC(=O)c1cc(OC(F)F)c(OC)cc1C(C(=O)OCC)C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 4/20 0.42
▸ NPSR1 Q6W5P4 2/20 0.42
▸ MAPT P10636 2/20 0.42
▸ GAA P10253 4/20 0.41
▸ LMNA P02545 3/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ GLA P06280 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ KMT2A Q03164 2/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ POLB P06746 1/20 0.38
▸ HSD17B2 P37059 1/20 0.38
▸ KDM1A O60341 1/20 0.38
▸ KCNK3 O14649 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25386161 0.82 LCK (0.49) DPP4NPSR1MAPTGAALMNA
SCHEMBL2339344 0.79 TSHR (0.49) DPP4MAPTGAALMNASMN1; SMN2
SCHEMBL30575766 0.79 DPP4 (0.43) DPP4NPSR1MAPTGAALMNA
SCHEMBL25387292 0.79 DPP4 (0.43) DPP4NPSR1MAPTGAALMNA
SCHEMBL15614381 0.78 KMT2A (0.49) DPP4MAPTGAALMNASMN1; SMN2
SCHEMBL11375450 0.77 KMT2A (0.45) DPP4NPSR1MAPTGAALMNA
SCHEMBL14914576 0.74 TSHR (0.47) DPP4MAPTGAALMNASMN1; SMN2
SCHEMBL31412877 0.74 TSHR (0.43) DPP4MAPTGAALMNASMN1; SMN2
SCHEMBL30575711 0.74 TSHR (0.43) DPP4MAPTGAALMNASMN1; SMN2
SCHEMBL13028013 0.73 KDM4E (0.56) MAPTGAALMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179087-A1 COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS Immunophage Biotech (Shanghai) Co., Ltd. (CN) 2025-06-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179087-A1 COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS LPAR5, LPAR3, LPAR2 DPP4 814/4885NPSR1 212/4885MAPT 3710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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