SCHEMBL25387802

SCHEMBL25387802

c1ccc(NC2CCC3CCCCC3C2C2C(Nc3ccccc3)CCC3CCCCC32)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.40
GFER P55789 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
TRPA1 O75762 1/20 0.35
CA1 P00915 1/20 0.35
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.33
HDAC4 P56524 2/20 0.33
EPHX2 P34913 2/20 0.33
EPHX1 P07099 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24426777 0.82 ALDH1A1 (0.49) ALDH1A1POLBGFERSMN1; SMN2LMNA
SCHEMBL22781478 0.82 ALDH1A1 (0.49) ALDH1A1POLBGFERSMN1; SMN2LMNA
SCHEMBL14609 0.82 ALDH1A1 (0.49) ALDH1A1POLBGFERSMN1; SMN2LMNA
SCHEMBL22271628 0.81 ALDH1A1 (0.47) ALDH1A1POLBGFERSMN1; SMN2LMNA
SCHEMBL30887532 0.75 ALDH1A1 (0.65) ALDH1A1POLBGFERSMN1; SMN2LMNA
SCHEMBL11854 0.68 ALDH1A1 (0.39) ALDH1A1POLBGFERSMN1; SMN2LMNA
SCHEMBL7634555 0.67 ALDH1A1 (0.51) ALDH1A1POLBGFERSMN1; SMN2LMNA
SCHEMBL4064616 0.67 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2LMNAGAA
SCHEMBL4065548 0.67 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2LMNAGAA
2-(Phenylamino)Cyclohexanol SCHEMBL432132 0.67 ALDH1A1 (0.51) ALDH1A1POLBGFERSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255105-A1 ORGANIC COMPOUNDS WITH DELAYED FLUORESCENCE EMISSION AND CIRCULARLY POLARISED LUMINESCENCE AND USE THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255105-A1 ORGANIC COMPOUNDS WITH DELAYED FLUORESCENCE EMISSION AND CIRCULARLY POLARISED LUMINESCENCE AND USE THEREOF TEAD2, TEAD4, AAAS ALDH1A1 503/4885POLB 1817/4885GFER 2359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.