Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TEAD2 | Q15562 | 3/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.39 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22271628 | 0.98 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2LMNAGAA | |
| SCHEMBL24426777 | 0.96 | ALDH1A1 (0.49) | ALDH1A1POLBSMN1; SMN2LMNAGAA | |
| SCHEMBL22781478 | 0.96 | ALDH1A1 (0.49) | ALDH1A1POLBSMN1; SMN2LMNAGAA | |
| SCHEMBL25387802 | 0.82 | ALDH1A1 (0.43) | ALDH1A1POLBSMN1; SMN2LMNAGAA | |
| SCHEMBL30887532 | 0.82 | ALDH1A1 (0.65) | ALDH1A1POLBSMN1; SMN2LMNAGAA | |
| SCHEMBL11854 | 0.80 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2LMNAGAA | |
| SCHEMBL11463891 | 0.80 | HCAR3 (0.43) | ALDH1A1LMNAGAAGFERRAB9A | |
| SCHEMBL11396540 | 0.76 | NPC1 (0.50) | ALDH1A1SMN1; SMN2LMNAGAAGFER | |
| SCHEMBL6481111 | 0.75 | SYK (0.43) | ALDH1A1SMN1; SMN2LMNAGAATEAD2 | |
| SCHEMBL14661 | 0.75 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345677-A2 | Technique for selecting polymerization modifiers | Dow Global Technologies LLC (US) | 2011-07-20 | — | — | EP | disclosed |
| WO-2011043954-A1 | NOVEL TRPA1 ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2011-04-14 | — | — | WO | disclosed |
| EP-1763542-B1 | TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS | DOW GLOBAL TECHNOLOGIES INC (US) | 2011-04-06 | — | — | EP | disclosed |