Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20306595 | 0.83 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL27864622 | 0.79 | F11 (0.32) | KMT2ADGAT1 | |
| SCHEMBL16387218 | 0.79 | NPC1 (0.33) | KMT2ADGAT1 | |
| SCHEMBL3079979 | 0.76 | F2 (0.34) | KMT2ADGAT1ALDH1A1 | |
| SCHEMBL23130519 | 0.73 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL27228003 | 0.71 | — | — | |
| SCHEMBL30496013 | 0.70 | — | — | |
| SCHEMBL23986534 | 0.70 | — | — | |
| SCHEMBL21631566 | 0.70 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL20489156 | 0.70 | DGAT1 (0.34) | DGAT1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173057-A1 | MEK INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023173057-A1 | MEK INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2023-09-14 | — | — | WO | disclosed |