SCHEMBL25389373

SCHEMBL25389373

CC(C)CNC(=O)C(C)(C)N1CCC(c2ccccc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 4/20 0.48
KCNH2 Q12809 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
SLC18A3 Q16572 3/20 0.42
DRD2 P14416 1/20 0.42
OPRM1 P35372 1/20 0.42
LIPE Q05469 1/20 0.42
ADRA1D P25100 1/20 0.42
ADRA1A P35348 1/20 0.42
ADRA1B P35368 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
CCR1 P32246 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26239083 0.95 PRCP (0.45) PRCPKCNH2HRH3SLC18A3DRD2
SCHEMBL26238974 0.88 CCR1 (0.44) KCNH2CCR1
SCHEMBL26238973 0.86 KCNQ2 (0.48) PRCPKCNH2LIPE
SCHEMBL26238904 0.84 SLC18A3 (0.44) PRCPKCNH2HRH3SLC18A3DRD2
SCHEMBL26238970 0.84 TRPV1 (0.44) KCNH2OPRM1
SCHEMBL26238901 0.83 DRD2 (0.48) SLC18A3DRD2ADRA1DADRA1AADRA1B
SCHEMBL26238969 0.83 CHRM4 (0.44) DRD2
SCHEMBL26238971 0.81 MEN1 (0.50) KCNH2DRD2
SCHEMBL26238902 0.81 KCNH2 (0.47) PRCPKCNH2HRH3OPRM1CCR1
SCHEMBL26238903 0.81 KCNH2 (0.47) PRCPKCNH2HRH3OPRM1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280861-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2025-09-11 US disclosed
EP-4472947-A1 SWEETENER COMPOSITIONS Firmenich Incorporated (US) 2024-12-11 EP disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 WO disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250280861-A1 SWEETENER COMPOSITIONS GPR119, TAS2R50, TAS2R30 PRCP 1490/4885KCNH2 3794/4885HRH3 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.