SCHEMBL25390971

SCHEMBL25390971

O=C(O)c1ccc(-c2ccccc2-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
DAO P14920 1/20 0.62
NAPRT Q6XQN6 1/20 0.62
TP53 P04637 1/20 0.60
SRD5A2 P31213 3/20 0.58
CES2 O00748 1/20 0.58
CES1 P23141 1/20 0.58
RXRA P19793 2/20 0.57
RARB P10826 1/20 0.57
RARG P13631 1/20 0.57
EGFR P00533 1/20 0.55
BCL2L1 Q07817 1/20 0.54
BAD Q92934 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
SCN2A Q99250 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36017 0.98 TSHR (0.59) TSHRDAONAPRTTP53SRD5A2
SCHEMBL31327313 0.98 TSHR (0.59) TSHRDAONAPRTTP53SRD5A2
SCHEMBL31236746 0.98 TSHR (0.59) TSHRDAONAPRTTP53SRD5A2
SCHEMBL28397371 0.95 EGFR (0.62) TSHRDAONAPRTTP53SRD5A2
SCHEMBL8923959 0.91 CA12 (0.67) TSHRDAONAPRTTP53SRD5A2
SCHEMBL28365092 0.88 NAPRT (0.59) TSHRDAONAPRTSRD5A2CES2
SCHEMBL29111668 0.88 PTPRC (0.65) TSHRDAONAPRTSRD5A2CES2
Terephthalic Acid SCHEMBL9337978 0.87 TSHR (0.72) TSHRDAONAPRTTP53SRD5A2
SCHEMBL2038730 0.87 HSD17B10 (0.64) TSHRDAONAPRTTP53SRD5A2
SCHEMBL29876739 0.87 HSD17B10 (0.64) TSHRDAONAPRTTP53SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240294675-A1 RING-OPENING METATHESIS POLYMERIZATION THE TRUSTEES OF BOSTON COLLEGE (US) 2024-09-05 US claimed
CN-118136938-A Polymer composite solid electrolyte, preparation method and application thereof 南方科技大学 2024-06-04 CN claimed
CN-114903028-B Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2023-10-17 CN claimed
US-20250188521-A1 NUCLEIC ACID DELIVERY SCAFFOLDS Singular Genomics Systems, Inc. 2025-06-12 US disclosed
EP-4566810-A1 ADHESIVE SEALING FILM FOR FUEL CELL Zacros Corporation (JP) 2025-06-11 EP disclosed
WO-2025033304-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL ALIGNMENT FILM, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-02-13 WO disclosed
US-12188088-B1 Multiplexed targeted amplification of polynucleotides Singular Genomics Systems, Inc. (US) 2025-01-07 US disclosed
US-20240425919-A1 MULTIPLEXED TARGETED AMPLIFICATION OF POLYNUCLEOTIDES FIRST-CITIZENS BANK & TRUST COMPANY 2024-12-26 US disclosed
US-20240342718-A1 MULTIPLEXED TARGETED AMPLIFICATION FOR MUTATION DETECTION FIRST-CITIZENS BANK & TRUST COMPANY 2024-10-17 US disclosed
US-20240294675-A1 RING-OPENING METATHESIS POLYMERIZATION THE TRUSTEES OF BOSTON COLLEGE (US) 2024-09-05 US disclosed
US-20240240251-A1 MULTIPLEXED TARGETED AMPLIFICATION OF POLYNUCLEOTIDES FIRST-CITIZENS BANK & TRUST COMPANY 2024-07-18 US disclosed
US-20230399692-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-12-14 US disclosed
US-11795505-B2 Nucleic acid delivery scaffolds Singular Genomics Systems, Inc. (US) 2023-10-24 US disclosed
US-20230287491-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-09-14 US disclosed
WO-2023172665-A2 NUCLEIC ACID DELIVERY SCAFFOLDS Singular Genomics Systems, Inc. (US) 2023-09-14 WO disclosed
CN-116589694-A Rubber asphalt VOCs inhibitor based on MOFs material, smoke suppression rubber asphalt and preparation method 武汉理工大学 2023-08-15 CN disclosed
EP-4177295-A1 RESIN COMPOSITION AND MOLDED ARTICLE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-05-10 EP disclosed
WO-2023076833-A1 MULTIPLEXED TARGETED AMPLIFICATION OF POLYNUCLEOTIDES Singular Genomics Systems, Inc. (US) 2023-05-04 WO disclosed
CN-112920223-B Catalyst for silicon cyanation reaction of aldehyde and trimethylsilyl cyanide and preparation method thereof 兰州大学 2022-09-20 CN disclosed
WO-2022071286-A1 LIQUID-CRYSTAL COMPOSITION, LIQUID-CRYSTAL DISPLAY ELEMENT PRODUCTION METHOD, AND LIQUID-CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2022-04-07 WO disclosed